We welcome you to join our workshop on NGS data analysis and visualization at the ESHG conference on Saturday June 23, 2012, from 11.45-13.15 hrs.
Lunch is our treat and the program will cover the topics of medical re-sequencing pipelines, trio analysis and streamlined amplicon sequencing - and you will of course get an introduction of how to use CLC Genomics Workbench for your human genetics data analysis.
Experts from Radboud University Hospital and University of Pittsburgh are invited as guest speakers, and together with our own experts, they will kick-start your stay at ESHG with some excitng presentations within the field of human genetics.
Please join us for lunch and science from 11.45-13.15 hrs on June 23 in Room “Helsinki” at Nürnberg Convention Center Ost.
We are looking forward to seeing you.
A result of the partnership between CLC bio and IBM has shown outstanding performance on sequence assembly and mapping – time-consuming analyses, highly demanding for computational power and storage.
De novo assembly of the human genome (37x coverage) using paired-end information is completed within 5 hours and 15 minutes using CLC Assembly Cell on IBM x3850 X5 with GPFS. Without using paired-end information it takes less than 5 hours and further optimization is obtained running the assembly with a file system RAM of 400GB.
Read mapping of a whole human genome is completed within just 13 minutes when running jobs in parallel using 37 IBM iDataPlex compute nodes with GPFS. This is done using a beta version* of our new read mapper that will soon be released with CLC Genomics Workbench, CLC Genomics Server and CLC Assembly Cell.
Read the detailed benchmarks in the IBM Solution Brief using CLC Assembly Cell
*The performance of the final version may change compared to the beta version.
Genomics Gateway is our integrated framework for analyzing large scale genomics data and the framework facilitates the visualization and comparison of different kinds of genomics data in a user-friendly way.
Genomics data can be filtered and annotated to discover genomic variants like SNVs and indels and the integration of commercial and public databases as, e.g., BIOBASE’s Genome Trax™ and Ensembl makes it easy to combine newly identified variants with existing knowledge.
Genomics Gateway also has a number of tools to combine and compare genomics data. For example, you can run the Fisher exact test to identify interesting disease-related variants in a case-control study or the GO-enrichment analysis tool can help you identify common molecular functions or biological processes of all altered genes in a sample.
Have a look at our new product sheet describing features and benefits of the Genomics Gateway framework here.
Reader’s Digest just published a new article, putting CLC bio’s hometown, Aarhus, as one of the 4 happiest cities on this planet together with Singapore, San Luis Obispo in California, and Monterrey in Mexico!
During the last half of the previous decade, news reports started coming out, stating that Denmark is the happiest country in the world. The attention peaked internationally when Oprah came to Denmark in 2009 and covered the subject. We still rank pretty high.
The article in Reader’s Digest mentions a 68% tax-rate and that is not accurate - it’s typically in the 40-50% range for most people working in Denmark, with a few below and above that. It’s worth noting that healthcare and free education are some of the benefits that are included with the taxes.
CLC bio’s home town Aarhus has been known as the happiest city within Denmark and with around 300000 residents and around 15% of those enrolled with the local university, it’s not hard to believe. Especially not, when you live and work here, within a 10-minute biking distance of forest, open fields, beach, and sea.
The location of Aarhus might also be the reason that it was founded during the Viking Age, and there are still traces of the people who settled by the mouth of the Aarhus river.
Looking for talent
We’re currently looking for people with the right skills and experience - e.g. three skilled Bioinformatics Scientists to come and work from our headquarters in Aarhus. If you are interested in becoming part of our innovative team, please go to clcbio.com and check our open job positions:
http://www.clcbio.com/careers
Note: We also have job openings in less happy cities - but you’ll still be part of a happy company!
We are continuously developing the CLC de novo assembly algorithm and our new assembler is an improvement over previous versions with better support for large data sets and integrated scaffolding for joining contigs based on paired reads information.
The white paper on our new de novo assembler includes some brand new performance benchmarks on genome assembly of E. Coli, A. thaliana and Homo sapiens, respectively.
The results demonstrate the assembler’s ability to produce accurate assemblies extremely fast using both standard consumer hardware and server systems. For example, the assembly of a high coverage dataset for the A. thaliana genome is completed in just half an hour on a quad-core laptop, while an assembly of the human genome using a 43x coverage dataset takes just seven hours on a quad-processor system.
Click to read the white paper on CLC Assembly Cell 4.0
